From minute one, the defender had a clear strategy to try to get physical with the little Argentine.
The Spaniard left his leg out to purposely trip Messi early in the first half.
He then went to ground himself pretending to be injured in an attempt to escape the referee’s sanctions.
But he was at it again moments later, leaving an elbow in the face of Messi who collapsed to the ground.
When Ramos went to check on the forward, the Barcelona star saw red.
Messi got in the face of Ramos as the pair went head to head.
He was clearly letting his feeling be known, likely to be that he felt Ramos knew what he was doing.
Ivan Rakitic gave Barcelona a first half lead when he chipped Thibaut Courtois.
Former Real Madrid boss Jose Mourinho told beIN Sports that Ramos was trying to get a message across with the incident.
“He probably does it with the intention of creating a different temperature for the second half because the game until now was really soft,” he said.
One fan tweeted: “Wow who wouldn’t thought.. Ramos throwing elbows. First time.”
Another said: “Is there such a thing as an unintentional elbow by Sergio Ramos?”
One Liverpool fan even got involved: “I hate Ramos, that was a blatant elbow on Messi, the things he gets away with.”
“Ramos elbows Messi in the face and gets nothing,” another fan tweeted.
Ramos was later booked in the second half, for a shoulder barge on Messi.
After the foul was given, he told the Barcelona man to get on his feet claiming that he was making the most of it.
Replays showed that it was a clear obstruction and the defender can count himself lucky that it took until this long for him to be carded.